学术报告三十三_Novel advanced plasmonic metamaterials for

发表于 2017-09-04 17:15

题目：Novel advanced plasmonic metamaterials for ultrasensitive biosensing

时间：2017年8月5日（周六）上午10点

地点：南校区光电工程学院1212会议室

报告人：Andrei V. Kabashin（Aix-Marseille University）

摘要：This presentation will overview our on-going activities on the improvement of physical sensitivity of plasmonic biosensors, which rely on the control of biological binding events between a target analyte and its corresponding receptor on the gold surface by refractive index (RI) monitoring. Our approach is based on the design of “plasmonic metamaterial for biosensing”, which were defined as “artificial materials, composed of nanoscale gold blocks (metaatoms) with nanoscale distance between them, which can provide a much improved response compared to natural plasmonic materials (Au, Au) and/or enable new functionalities” [1]. One of geometries of such metamaterial uses a "forest" of long gold nanorods (length 300-500 nm, width 20-40 nm, rod-to-rod distance 20-60 nm), oriented perpendicularly to the glass substrate. Such plasmonic nanorod metamaterial is capable of supporting a new guided mode, which propagates over discontinuous "forest" structure and in terms of sensitivity (> 30000 nm/RI units) outperforms both localized plasmon resonance (LPR) and surface plasmon resonance (SPR) biosensors [1]. In addition, porous "nanorod forest" structure increases the final sensitivity as much more biomaterial can be immobilized inside it. Another promising metamaterial is based on a periodic array of gold nanodots (~100 nm in size), which makes possible the excitation of diffraction-coupled localized plasmons, leading to a drastic narrowing of resonance width and nearly zero light intensity in it (“light darkness”) [2]. As a consequence of this darkness, phase of light starts to experience extreme Heaviside-like jumps near the resonance minimum [3,4], which can be used to improve an areal mass sensitivity down to the record 1 fg/mm-2 level corresponding to singular molecule label-free detection [2]. We also for the first time explored the excitation of plasmons in 3D plasmon crystal metamaterials and reported the observation of a guiding plasmon mode, which provided extremely high spectral sensitivity to refractive index variations, outperforming all plasmonic counterparts excited in 2D nanoscale geometries [5]. We finally proposed novel graphene-gold metasurface architectures, which render possible the improvement of sensor response in conventional SPR due to the concentration of local electric field on the graphene sheet and specific graphene-related chemistry [6]. As an example, the recorded 10-18 M level for the detection of single stranded DNA, which is 3 orders of magnitude better than any state-of-the-art plasmonic sensor. Depending on a concrete biosensing task, the metamaterials can be designed either to record several binding events (a way toward ultimate label-free single molecular detection) or to enable large surface coverage in order to improve integral sensitivity. Combined with tuneable spectral response and strong local field enhancement, the designed biosensors outperform conventional plasmonics-based counterparts and open up new opportunities for the advancement of current state-of-the-art biosensing technology.

[1] A. V. Kabashin,  P. Evans, S. Patskovsky, G. Wurtz, W. Hendren, W. Dickson, R. J. Pollard, V. Podolsky, A. V. Zayats A. V., Nature Mater. 2009, 8, 867-871

[2] V. G. Kravets, F. Schedin, R. Jalil, L. Britnell, R. V. Gorbachev, D. Ansell, B. Thackray, K. S. Novoselov, A. K. Geim, A. V. Kabashin, A. N. Grigorenko, Nature Mater. 2013, 12, 304-309.

[3] A. V. Kabashin, S. Patskovsky, A. N. Grigorenko, Opt. Express 2009, 17, 21191-21204.

[4] Y. H. Huang, H.-P. Ho, K. S. Kong, A. V. Kabashin, Annal. der Physik, 2012, 524, 637.

[5] A. I. Aristov, M. Manousidaki, A. Danilov, K. Terzaki, C. Fotakis, M. Farsari, A. V. Kabashin, Sci. Rep., 2016, 6, 25380

[6] S. Zeng, K. V. Sreekanth, J. Shang, T. Yu, C.-K. Chen, F. Yin, D. Baillargeat, P. Coquet, H.-P. Ho, A. V. Kabashin, K.-T. Yong Adv. Mater., 2015, 27, 6163.

报告人简介：Prof. A. V. Kabashin is one of world leading experts in plasmonics/metamaterial-based biosensing and laser-ablative nanofabrication. He obtained his MS Degree in 1990 from Moscow Institute of Physics and technology (MIPT) and his Ph.D. degree in 1994 from A.M. Prokhorov General Physics Institute, Moscow, Russia. From 1999 to 2008 he worked as Research Professor of the University of Montreal, Canada. Since 2009 he holds a Research Director position of the French National Center of Scientific Research (CNRS) in Aix-Marseille University, Marseille, France. He is also a Scientific Director of the Institute of Engineering Physics for Biomedicine (PhysBio) and the Head of International Laboratory “Bionanophotonics” of the National Nuclear Research University (MEPhI), Moscow, Russia. Finally, he holds an Adjunct Professorship in the Institute of Lasers, Photonics and Biophotonics in State University of New York at Buffalo (USA) and an Associate Professorship the University of Sherbrooke (Canada)